Product Description
Mechanisms of Action: Immunosuppressive
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Percutaneous
FDA Designation: *
Approval Status: Not Approved
Approved Countries: Australia | Colombia
Approved Indications: None
Known Adverse Events: None
Company: PaceMate
Company Location: Eastern America
Company Founding Year: None
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Recent & Upcoming Milestones
Highest Development Phases
Phase 4: Coronary Artery Disease|Myocardial Ischemia|Myocardial Infarction|Coronary Stenosis|Angina, Stable|Angina Pectoris|Acute Coronary Syndrome|Thrombosis|Inflammation|Coronary Restenosis|Angina, Unstable|Coronary Disease|ST Elevation Myocardial Infarction
Phase 3: Myocardial Ischemia|Coronary Artery Disease|Arteriosclerosis|Coronary Occlusion|Coronary Stenosis
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT05340361 |
ONYSOVER | N/A |
Recruiting |
Coronary Artery Disease |
2026-12-31 |
2025-11-26 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments |
|
ChiCTR2500114166 |
ChiCTR2500114166 | N/A |
/Completed |
Unknown |
2025-12-31 |
|||
NCT05240781 |
ZEVS-HBR | N/A |
Unknown status |
Coronary Artery Disease |
2024-02-28 |
2025-03-04 |
Primary Endpoints|Treatments|Trial Status |
|
NCT04885816 |
DEBORA | N/A |
Terminated |
Myocardial Ischemia|Coronary Artery Disease |
2021-09-29 |
2021-10-27 |
||
NCT04825886 |
CNUH-2017-319 | N/A |
Completed |
Myocardial Ischemia|Coronary Artery Disease |
2021-03-18 |
2024-02-07 |
||
NCT03471845 |
MDT16058RES004 | N/A |
Active, not recruiting |
Myocardial Ischemia|Coronary Artery Disease|Arteriosclerosis |
2021-02-24 |
2021-10-15 |
Primary Endpoints|Study Completion Date|Treatments |
|
NCT03466151 |
MDT16061RES005 | N/A |
Active, not recruiting |
Myocardial Ischemia|Arteriosclerosis|Coronary Artery Disease |
2021-02-12 |
2021-10-15 |
Primary Endpoints|Study Completion Date|Treatments |
|
NCT01735656 |
the DK Culotte-I Study | N/A |
Completed |
Coronary Artery Disease|Myocardial Ischemia |
2020-12-01 |
2022-09-28 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT02098876 |
SHEAR-STENT | N/A |
Completed |
Coronary Artery Disease |
2020-12-01 |
2025-08-27 |
||
NCT03584464 |
Bifurcation Cohort | N/A |
Completed |
Coronary Artery Disease |
2020-11-04 |
2023-05-02 |
Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT03647475 |
Onyx ONE Clear | N/A |
Completed |
Coronary Artery Disease |
2020-03-10 |
2021-05-07 |
Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT03376646 |
CL-VP-02 | N/A |
Completed |
Coronary Disease |
2020-01-10 |
2025-02-21 |
Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT03063749 |
ONYX PAS | N/A |
Completed |
Coronary Artery Disease |
2018-10-20 |
2022-10-28 |
Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT03344653 |
Onyx ONE | N/A |
Completed |
Coronary Artery Disease |
2018-09-27 |
2020-12-03 |
Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT03118531 |
MDT16003RES001 | N/A |
Completed |
Coronary Artery Disease|Arteriosclerosis|Myocardial Ischemia |
2018-07-31 |
2023-10-11 |
||
NCT02770651 |
APPOSITION-AMI II | N/A |
Unknown status |
Arteriosclerosis|Coronary Artery Disease|Arterial Occlusive Diseases|Myocardial Ischemia |
2018-06-01 |
2020-01-04 |
Primary Endpoints|Treatments|Trial Status |
|
NCT03151018 |
HOST-ONYX | N/A |
Unknown status |
Angina Pectoris|Coronary Artery Disease|Myocardial Ischemia|Acute Coronary Syndrome|Myocardial Infarction |
2018-05-01 |
2021-05-04 |
Primary Endpoints|Treatments|Trial Status |
|
NCT01397175 |
CHOICE | N/A |
Terminated |
Coronary Artery Disease|Myocardial Ischemia |
2017-12-05 |
2019-07-10 |
Primary Completion Date|Start Date|Study Completion Date|Treatments|Trial Status |
|
NCT01747356 |
RESOLUTE-DM | N/A |
Completed |
Coronary Artery Disease|Myocardial Ischemia |
2015-11-01 |
2019-03-19 |
Treatments |
|
NCT02452736 |
CHINA RESOLUTE INTEGRITY STUDY | P3 |
Completed |
Myocardial Ischemia|Arteriosclerosis|Coronary Artery Disease |
2015-08-01 |
2019-03-20 |
Treatments |
|
NCT00693251 |
PERFECT | P4 |
Completed |
Coronary Artery Disease|Myocardial Ischemia |
2015-06-01 |
2019-03-18 |
Treatments |
|
NCT00694005 |
CROSS | P4 |
Completed |
Myocardial Ischemia|Coronary Artery Disease |
2015-01-01 |
2019-03-18 |
||
NCT01781715 |
ZES for STEMI | P4 |
Unknown status |
Myocardial Ischemia|ST Elevation Myocardial Infarction|Coronary Artery Disease |
2013-12-01 |
2019-03-19 |
Treatments |
|
NCT01563952 |
CTO | P4 |
Unknown status |
Myocardial Ischemia|Coronary Artery Disease |
2013-10-01 |
2019-03-19 |
Treatments |
|
NCT02018991 |
MUW-0001 | P4 |
Completed |
Thrombosis|Inflammation |
2013-08-01 |
2019-03-20 |
Treatments |