Product Description
Mechanisms of Action: NK1 Antagonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous, Oral
FDA Designation: *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: GSK
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Depressive Disorder|Insomnia|Tinnitus|Parasomnias|Generalized anxiety disorder|Hearing Loss|Phobia, Social|Anesthesia Related|Deafness|Other
Phase 1: Healthy Volunteers
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|
| VNK114995 | P1 |
Completed |
Healthy Volunteers |
2011-10-01 |
2019-03-19 |
||
| 2011-005216-28 | P2 |
Terminated |
Unknown |
2012-08-22 |
2022-03-13 |
Treatments |
|
| VNK115640 | P2 |
Completed |
Other |
2012-08-01 |
2024-10-16 |
Primary Endpoints |
|
| 2008-006345-72 | P2 |
Completed |
Insomnia |
2009-09-21 |
2022-03-13 |
Treatments |
|
| NCT00992160 | P2 |
Completed |
Parasomnias |
2009-09-01 |
2019-03-19 |
Treatments |
|
| 2006-003295-36 | P2 |
Completed |
Tinnitus |
2009-08-06 |
2022-03-12 |
Treatments |
|
| NKP106254 | P2 |
Completed |
Deafness|Tinnitus|Hearing Loss |
2009-08-01 |
2019-03-21 |
Treatments |
|
| 2007-004035-35 | P2 |
Completed |
Insomnia |
2008-05-07 |
2022-03-12 |
Treatments |
|
| NKI110334 | P2 |
Completed |
Insomnia |
2008-05-07 |
2019-03-18 |
||
| NKO101287 | P2 |
Completed |
Unknown |
2006-07-01 |
2019-03-22 |
Treatments |
|
| NKP102280 | P2 |
Completed |
Depressive Disorder |
2005-11-01 |
2019-03-21 |
Treatments |
|
| 2004-001894-24 | P2 |
Completed |
Generalized anxiety disorder |
2005-10-07 |
2022-03-12 |
Treatments |
|
| 2004-001021-22 | P2 |
Completed |
Anesthesia Related |
2005-07-27 |
2022-03-12 |
Treatments |
|
| NKP103401 | P2 |
Completed |
Phobia, Social |
None |
2019-03-21 |
Treatments |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
08/13/2021 |
PubMed |
Efficacy of pharmacologic treatment in tinnitus patients without specific or treatable origin: A network meta-analysis of randomised controlled trials. |
|
10/19/2020 |
PubMed |
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis. |
|
10/18/2019 |
News Article |
Global Tinnitus Pipeline Insights 2019 |