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Torcetrapib

Alternative Names: torcetrapib
Latest Update: 2024-01-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: CETP Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Pfizer
Company Location: NEW YORK NY 10017
Company CEO: Albert Bourla
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Torcetrapib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Hypercholesterolemia|Hyperlipidemia|Hyperlipoproteinemia Type II|Hyperlipoproteinemias|Coronary Artery Disease|Hyperlipoproteinemia Type III|Dyslipidemia|Hyperlipoproteinemia Type IV|Coronary Disease|Hypertriglyceridemia

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
ILLUMINATE

P3

Terminated

Coronary Artery Disease

2007-06-01

2004-000156-16

P3

Terminated

Coronary Disease

2006-12-02

A5091031

P3

Terminated

Hyperlipidemia|Dyslipidemia|Hypercholesterolemia|Hyperlipoproteinemias

2006-12-01

A5091024

P3

Terminated

Hyperlipidemia|Hyperlipoproteinemias|Hyperlipoproteinemia Type III

2006-12-01

Recent News Events

Date

Type

Title

01/01/2024

PubMed

 Using TransR to enhance drug repurposing knowledge graph for COVID-19 and its complications.

04/01/2023

PubMed

 Structure-based mechanism and inhibition of cholesteryl ester transfer protein.

02/01/2022

PubMed

 Pharmacological Inhibition of CETP (Cholesteryl Ester Transfer Protein) Increases HDL (High-Density Lipoprotein) That Contains ApoC3 and Other HDL Subspecies Associated With Higher Risk of Coronary Heart Disease.

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