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Tazobactam

Alternative Names: tazobactam, zosyn, zerbaxa
Latest Update: 2024-12-18
Latest Update Note: News Article

Product Description

Piperacillin and tazobactam combination injection is used to treat bacterial infections in many different parts of the body (eg, stomach or bowel, lungs, skin, female reproductive organs). (Sourced from: https://www.mayoclinic.org/drugs-supplements/piperacillin-and-tazobactam-intravenous-route/description/drg-20072716)

Mechanisms of Action: LACTB Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Argentina | Australia | Austria | Bangladesh | Belgium | Brazil | Bulgaria | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Russia | Saudi Arabia | Serbia | South Africa | Spain | Sri Lanka | Sweden | Taiwan | Thailand | Tunisia | Turkey | United Arab Emirates | United Kingdom | United States | Venezuela | Vietnam

Approved Indications: Pneumonia, Bacterial | Pelvic Infection | Pneumonia | Urinary Tract Infections | Nephritis | Pyelonephritis

Known Adverse Events: Headache | Insomnia | Constipation | Diarrhea

Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Tazobactam

Countries in Clinic: Chile, China, Colombia, Estonia, Greece, Mexico, Russia, Spain, Ukraine, United States

Active Clinical Trial Count: 9

Highest Development Phases

Phase 3: Enterobacteriaceae Infections|Pneumonia

Phase 2: Bacteremia|Bronchiectasis|Bronchitis, Chronic|Chronic Obstructive Pulmonary Disease|Coinfection|Community-Acquired Infections|Pseudomonas Infections|Pyelonephritis|Respiratory Tract Infections|Urinary Tract Infections

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

NCT04673175

P2

Recruiting

Pseudomonas Infections|Pneumonia|Bacteremia

2025-12-31

2022-002636-31

P3

Active, not recruiting

Enterobacteriaceae Infections

2025-12-09

MK-7625A-036

P1

Completed

Pneumonia

2024-09-14

2018-004704-19

P1

Active, not recruiting

Pneumonia

2022-12-08

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