Ozmosi | Tarenflurbil Drug Profile

Product Description

Mechanisms of Action: JNK Activator

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral, Topical

FDA Designation: *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Company: Fraunhofer Gesellschaft
Company Location:
Company Founding Year: None
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Recent & Upcoming Milestones

Highest Development Phases

Phase 3: Alzheimer Disease

Phase 2: Dermatitis, Atopic|Prostate Cancer|Multiple Sclerosis, Relapsing-Remitting|Skin Cancer|Melanoma

Phase 1: Healthy Volunteers

Trial ID	Trial	Phase	Trial Status	Disease	Primary Completion Date	Latest Trial Update Date	Data Updated
NCT02206854	FLIP0112	P1	Completed	Healthy Volunteers	2014-09-01	2019-03-20	Treatments
2014-004483-38	2014-004483-38	P2	Completed	Multiple Sclerosis, Relapsing-Remitting	2018-04-20	2025-07-09	Treatments
NCT02686788	TMP001_MS	P2	Completed	Multiple Sclerosis, Relapsing-Remitting	2018-04-01	2019-03-20	Treatments
2011-002571-42	2011-002571-42	P2	Completed	Dermatitis, Atopic	2012-04-19	2025-07-02	Treatments
NCT00045123	CDR0000256371	P2	Unknown status	Prostate Cancer	None	2019-03-21	Treatments
ACTRN12606000192583	ACTRN12606000192583	P2	Completed	Skin Cancer\|Melanoma	None	2026-02-15	Treatments
2006-000654-43	2006-000654-43	P3	Completed	Alzheimer Disease	2008-10-31	2022-03-12	Treatments
NCT00322036	MPC-7869-05-010.01	P3	Terminated	Alzheimer Disease	None	2019-03-21	Treatments
NCT00105547	MPC-7869-04-005.02	P3	Completed	Alzheimer Disease	None	2019-03-21	Treatments
NCT00380276	MPC-7869-05-009	P3	Terminated	Alzheimer Disease	None	2019-03-21	Treatments
2007-003362-17	2007-003362-17	P3	Active, not recruiting	Alzheimer Disease	None	2022-03-12	Treatments

Recent News Events

Date	Type	Title
06/15/2023	PubMed	Topological effects in ultrafast photoinduced processes between flurbiprofen and tryptophan in linked dyads and within human serum albumin.
04/01/2023	PubMed	Comparison of in vivo pharmacokinetic behaviors of R- and S-flurbiprofen after intravenous injection of flurbiprofen axetil.
06/01/2022	PubMed	Comparison of percutaneous permeation profiles of flurbiprofen enantiomers.

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Tarenflurbil

Alternative Names: tarenflurbil, r-flurbiprofen, mpc-7869, TMP-001, TMP001, TMP 001 Clinical Status: Inactive Latest Update: 2023-06-15 Latest Update Note: PubMed Publication