Ozmosi | RPH-001 Drug Profile

Product Description

Bevacizumab Biosimilar

Mechanisms of Action: VEGF Inhibitor

Novel Mechanism: No

Modality: Antibody

Route of Administration: Intravenous

FDA Designation: *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: TRPHARM
Company Location: Europe
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Recent & Upcoming Milestones

Highest Development Phases

Phase 3: Colorectal Cancer|Liver Cancer

Trial ID	Trial	Phase	Trial Status	Disease	Primary Completion Date	Probability of Success	Latest Trial Update Date	Data Updated
NCT05238831	STUDY00020679	P1	Withdrawn	Soft Tissue Cancer\|Prostate Cancer\|Sarcoma\|Pancreatic Cancer\|Ovarian Cancer\|Breast Cancer	2026-05-31	4%	2024-11-27	Primary Endpoints\|Treatments
NCT03878524	PRIME	P1	Terminated	Pancreatic Cancer\|Acute Myelomonocytic Leukemia\|Preleukemia\|Myelodysplastic Syndrome\|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma\|Thrombocytosis\|Chronic Lymphoid Leukemia\|Myeloid, Accelerated Leukemia\|Breast Diseases\|Precursor Cell Lymphoblastic Leukemia-Lymphoma\|Acute Myeloid Leukemia\|Lymphocytic Chronic B-Cell Leukemia\|Acute Lymphoid Leukemia\|Prostate Cancer\|Myelodysplastic-Myeloproliferative Diseases\|Breast Cancer\|Multiple Myeloma\|Myelofibrosis\|Chronic Myeloid Leukemia\|Lymphoma, B-Cell\|Myeloproliferative Disorders\|Lymphoma, Non-Hodgkin\|Leukemia, Plasma Cell\|Chronic, Atypical, BCR-ABL Negative Myeloid Leukemia\|Blast Crisis\|Juvenile Myelomonocytic Leukemia,\|Adenocarcinoma\|Acute Monocytic Leukemia\|Chronic Myelomonocytic Leukemia\|Myelogenous, Chronic, BCR-ABL Positive Leukemia\|Anemia, Refractory	2020-12-10		2024-11-27	Primary Endpoints\|Treatments
NCT03659305	СL01011063	P1	Completed	Healthy Volunteers\|Oncology Unspecified	2019-01-26	64%	2019-03-22	Primary Completion Date\|Study Completion Date\|Treatments\|Trial Status
NCT03131700	RPH001BEV01	P1	Withdrawn	Healthy Volunteers	2018-01-01		2019-03-21	Treatments
2017-001634-26	2017-001634-26	P1	Unknown status	Non-Small-Cell Lung Cancer	2017-05-29		2025-06-20	Primary Completion Date\|Start Date\|Study Completion Date\|Treatments\|Trial Status
NCT07288034	IMMUNO-BIOMAP	P2	Not yet recruiting	Non-Small-Cell Lung Cancer	2028-09-22		2025-12-18	Primary Endpoints\|Treatments
NCT05001880	NCI-2021-08573	P2	Recruiting	Mesothelioma	2026-08-20		2025-10-10	Primary Completion Date\|Primary Endpoints\|Study Completion Date
NCT02364713	MC1365	P2	Terminated	Mucinous Adenocarcinoma\|Transitional Cell Carcinoma\|Ovarian Cancer\|Peritoneal Cancer\|Clear Cell Sarcoma\|Carcinosarcoma\|Clear Cell Adenocarcinoma\|Endometrioid Carcinoma	2022-01-13		2025-08-27	Patient Enrollment\|Primary Completion Date\|Primary Endpoints\|Study Completion Date\|Treatments\|Trial Status
NCT05863195	The PUMP Trial	P3	Recruiting	Liver Cancer\|Colorectal Cancer	2029-06-30		2024-11-27	Primary Endpoints\|Treatments

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RPH-001

Alternative Names: rph-001, rph001, rph 001 Clinical Status: Inactive Latest Update: 2025-12-17 Latest Update Note: Clinical Trial Update