Product Description
Rolapitant is a highly selective neurokinin-1 (NK-1) receptor antagonist with very good oral activity, central nervous system penetration and a long (180-hour) plasma half-life. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/28393710/)
Mechanisms of Action: NK1 Antagonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Belgium | European Medicines Agency | France | Germany | Hungary | Ireland | Italy | Lithuania | Poland | Portugal | Spain | Sweden | United Kingdom | United States
Approved Indications: Oncology Unspecified
Known Adverse Events: Dizziness | Neutropenia | Hiccup
Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: China
Active Clinical Trial Count: 1
Highest Development Phases
Phase 1: Healthy Volunteers
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
CTR20212383 | P1 |
Not yet recruiting |
Healthy Volunteers |
None |