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Ridaforolimus

Alternative Names: ridaforolimus, mk-8669, ap23573, mk8669
Latest Update: 2024-06-11
Latest Update Note: News Article

Product Description

Mechanisms of Action: mTOR Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Ridaforolimus

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Sarcoma|Osteosarcoma|Bone Cancer|Soft Tissue Cancer

Phase 2: Myeloid Leukemia|Myelodysplastic Syndrome|Lymphoma|Myelofibrosis|Prostate Cancer|Sarcoma|Oncology Unspecified|Liposarcoma|Leiomyosarcoma|Osteosarcoma|Endometrial Cancer|Non-Small-Cell Lung Cancer|Breast Cancer

Phase 1: Non-Small-Cell Lung Cancer|Sarcoma|Heart Cancer|Ovarian Cancer|Glioblastoma|Lymphoma|Breast Cancer|Oncology Unspecified|Endometrial Cancer|Multiple Myeloma|Oncology Solid Tumor Unspecified|Glioma|Gliosarcoma|Prostate Cancer|Colorectal Cancer|Primary Central Nervous System Lymphoma|Hepatic Insufficiency|Fallopian Tube Cancer|Liver Failure|Peritoneal Cancer

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
IoNIR-002

N/A

Not yet recruiting

Coronary Artery Disease|Coronary Stenosis

2025-09-01

CHAMPIONSHIP

N/A

Not yet recruiting

Peripheral Arterial Disease

2025-08-30

IonMAN

N/A

Recruiting

Non-ST Elevated Myocardial Infarction|Coronary Stenosis|Coronary Disease

2023-12-01

EluNIR-005

N/A

Completed

Coronary Stenosis|Myocardial Ischemia

2021-11-02

Recent News Events

Date

Type

Title

06/11/2024

News Article

 Nimble Announces Formation of a World-Class Scientific Advisory Board

03/22/2024

PubMed

 Clinical research progress of ridaforolimus (AP23573, MK8668) over the past decade: a systemic review.

01/16/2024

PubMed

 Percutaneous Coronary Interventions Using a Ridaforolimus-Eluting Stent in Patients at High Bleeding Risk.

01/01/2024

PubMed

 Percutaneous coronary intervention with ridaforolimus eluting-stents in small vessel coronary artery disease.

09/05/2023

News Article

 The Drug Coated Stent market size and share analysis provides a comprehensive picture of the market's projected CAGR of 12.8% from 2023 to 2030 through its analysis of market segmentation, sales volume, and share.

10/19/2022

News Article

 Drug Eluting Stent Market is estimated to be US$ 14.02 billion by 2032 with a CAGR of 6.5% during the forecast period 2032 - By PMI

07/30/2019

News Article

 North American Companion Diagnostics Devices Market 2019-2024 - Rising Demand & Awareness for Personalized Medicine & Targeted Therapy Drives Market Growth - ResearchAndMarkets.com

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