Product Description
Mechanisms of Action: Akt Inhibitor,PI3K Modulator
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: AEterna Zentaris
Company Location: MONTREAL A8 H3B 3V2
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Colorectal Cancer|Multiple Myeloma
Phase 2: Prostate Cancer|Waldenstrom Macroglobulinemia|Adenocarcinoma|Pancreatic Cancer|Breast Cancer|Leukemia|Colorectal Cancer|Renal Cell Carcinoma|Cervical Cancer|Lymphoma|Kidney Cancer|Multiple Myeloma|Astrocytoma|Ovarian Cancer|Oligodendroglioma|Non-Small-Cell Lung Cancer|Gliosarcoma|Brain Cancer|Glioblastoma|Sarcoma|Glioma|Lymphocytic Chronic B-Cell Leukemia|Alveolar Soft Part Sarcoma|Chronic Lymphoid Leukemia|Chondrosarcoma|Endometrial Cancer|Melanoma|Lymphoma, B-Cell|Head and Neck Cancer|Gastrointestinal Stromal Tumors
Phase 1: Multiple Myeloma|Preleukemia|Acute Megakaryoblastic Leukemia|Acute Lymphoid Leukemia|Liver Cancer|Colorectal Cancer|Kidney Cancer|Chronic Myeloid Leukemia|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Acute Monocytic Leukemia|Acute Promyelocytic Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic-Myeloproliferative Diseases|Diarrhea|Prostate Cancer|Renal Cell Carcinoma|Myelodysplastic Syndrome|Chronic Lymphoid Leukemia|Myeloproliferative Disorders|Myeloid, Accelerated Leukemia|Acute Myelomonocytic Leukemia|Adult T-Cell Leukemia-Lymphoma|Acute Myeloid Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Acute Erythroblastic Leukemia|Oncology Solid Tumor Unspecified|Blast Crisis|Hypokalemia|Angina, Unstable|Hypertrophy, Left Ventricular|Ovarian Cancer|Lymphoma|Neuroblastoma|Hepatitis C, Chronic|Hepatitis B, Chronic|Glioblastoma|Contraception|Surgical Wound Infection|Angina Pectoris|Heart Failure, Acute|Angina, Stable|Heart Failure, Chronic|Myocardial Infarction|Pregnancy Outcomes|HIV Infections|Torsades de Pointes|Brain Cancer|Neuromyelitis Optica|Astrocytoma|Oligodendroglioma
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
NCT00590954 | P2 |
Completed |
Glioma|Brain Cancer |
2019-11-11 |
|
NCI-2011-01409 | P2 |
Completed |
Oligodendroglioma|Gliosarcoma|Glioblastoma|Astrocytoma |
2018-11-16 |
|
AAAM3801 | P1 |
Completed |
Astrocytoma|Glioblastoma|Oligodendroglioma|Brain Cancer |
2017-10-27 |
|
NCT00776867 | P1 |
Completed |
Oncology Solid Tumor Unspecified |
2017-07-01 |