Product Description
Mechanisms of Action: Akt Inhibitor,PI3K Modulator
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: AEterna Zentaris
Company Location: MONTREAL A8 H3B 3V2
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Multiple Myeloma|Colorectal Cancer
Phase 2: Leukemia|Prostate Cancer|Waldenstrom Macroglobulinemia|Lymphocytic Chronic B-Cell Leukemia|Chronic Lymphoid Leukemia|Colorectal Cancer|Renal Cell Carcinoma|Lymphoma|Lymphoma, B-Cell|Oligodendroglioma|Endometrial Cancer|Multiple Myeloma|Glioblastoma|Melanoma|Non-Small-Cell Lung Cancer|Sarcoma|Adenocarcinoma|Gliosarcoma|Head and Neck Cancer|Pancreatic Cancer|Brain Cancer|Glioma|Astrocytoma|Gastrointestinal Stromal Tumors|Cervical Cancer|Kidney Cancer|Alveolar Soft Part Sarcoma|Breast Cancer|Chondrosarcoma|Ovarian Cancer
Phase 1: Heart Failure, Acute|Angina, Stable|Heart Failure, Chronic|Hepatitis B, Chronic|Hepatitis C, Chronic|Hypokalemia|HIV Infections|Torsades de Pointes|Angina Pectoris|Hypertrophy, Left Ventricular|Angina, Unstable|Pregnancy Outcomes|Myocardial Infarction|Renal Cell Carcinoma|Multiple Myeloma|Surgical Wound Infection|Contraception|Liver Cancer|Oncology Solid Tumor Unspecified|Colorectal Cancer|Kidney Cancer|Neuromyelitis Optica|Myelodysplastic-Myeloproliferative Diseases|Lymphoma|Myelodysplastic Syndrome|Preleukemia|Myeloproliferative Disorders|Prostate Cancer|Diarrhea|Astrocytoma|Acute Lymphoid Leukemia|Oligodendroglioma|Acute Myeloid Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Acute Megakaryoblastic Leukemia|Chronic Myeloid Leukemia|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Chronic Lymphoid Leukemia|Myeloid, Accelerated Leukemia|Acute Myelomonocytic Leukemia|Adult T-Cell Leukemia-Lymphoma|Glioblastoma|Neuroblastoma|Blast Crisis|Brain Cancer|Acute Promyelocytic Leukemia|Chronic Myelomonocytic Leukemia|Acute Monocytic Leukemia|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Acute Erythroblastic Leukemia|Ovarian Cancer
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
NCT00590954 | P2 |
Completed |
Glioma|Brain Cancer |
2019-11-11 |
|
NCI-2011-01409 | P2 |
Completed |
Astrocytoma|Oligodendroglioma|Glioblastoma|Gliosarcoma |
2018-11-16 |
|
AAAM3801 | P1 |
Completed |
Astrocytoma|Oligodendroglioma|Brain Cancer|Glioblastoma |
2017-10-27 |
|
NCT00776867 | P1 |
Completed |
Oncology Solid Tumor Unspecified |
2017-07-01 |