Product Description
Oritavancin is a lipoglycopeptide with bactericidal activity against gram-positive bacteria. (Sourced from: https://www.nejm.org/doi/full/10.1056/nejmoa1310422)
Mechanisms of Action: Cell Wall Inhibitor
Novel Mechanism: No
Modality: Peptide/Protein
Route of Administration: Intravenous
FDA Designation: *
Approval Status: Approved
Approved Countries: Austria | Belgium | Croatia | Czech | Estonia | European Medicines Agency | Finland | Germany | Greece | Hungary | Iceland | Ireland | Italy | Jordan | Latvia | Lithuania | Poland | Portugal | Saudi Arabia | Slovakia | Spain | Sweden | Switzerland | United Kingdom | United States
Approved Indications: None
Known Adverse Events: None
Company: Melinta
Company Location:
Company Founding Year: 2000
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Bulgaria, Greece, Latvia, Lithuania, Poland, Portugal, Romania, Spain, United States
Active Clinical Trial Count: 3
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Other
Phase 1: Gram-Positive Bacterial Infections
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT02134301 |
TMC-ORI-11-01 | P1 |
Completed |
Gram-Positive Bacterial Infections |
2025-11-04 |
50% |
2025-12-13 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments|Trial Status |
NCT05599295 |
ML-ORI-201 | P2 |
Completed |
Other |
2025-11-20 |
2% |
2025-11-26 |
|
2024-516385-10-00 |
ML-ORI-201 | P2 |
Not yet recruiting |
Unknown |
2025-06-30 |
2% |
2025-05-02 |
Treatments |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
02/12/2026 |
News Article |
CorMedix to Participate in Upcoming Investor Conferences |
|
02/02/2026 |
News Article |
CorMedix Therapeutics Announces Share Repurchase Program |
|
01/29/2026 |
News Article |
CorMedix Therapeutics to Host In-Person and Virtual Analyst Day in New York on February 10, 2026 |
|
01/09/2026 |
News Article |
CorMedix Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference |