Product Description
a signal transducer and activator of transcription 3 phosphorylation inhibitor for patients with relapsed or refractory hematological malignancies (Sourced from: https://pubmed.ncbi.nlm.nih.gov/25912076/)
Mechanisms of Action: STAT3 Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Otsuka
Company Location: NEW YORK NY 10271
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Recent & Upcoming Milestones
Highest Development Phases
Phase 1: Acute Lymphoid Leukemia|Multiple Myeloma|Lymphoma, Non-Hodgkin|Chronic Myeloid Leukemia|Acute Myeloid Leukemia|Chronic Lymphoid Leukemia|Non-Small-Cell Lung Cancer|Leukemia, Plasma Cell|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Melanoma|Small Cell Lung Cancer|Gastrointestinal Cancer|Gastrointestinal Stromal Tumors|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Acute Respiratory Distress Syndrome|Nasopharyngeal Cancer|Mouth Cancer
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|
| NP01/27/13 | P1 |
Terminated |
Nasopharyngeal Cancer |
2015-05-01 |
2019-03-20 |
Treatments |
|
| JapicCTI-111478 | P1 |
Completed |
Leukemia, Plasma Cell|Chronic Myeloid Leukemia|Multiple Myeloma|Acute Lymphoid Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Chronic Lymphoid Leukemia|Acute Myeloid Leukemia|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Lymphoma, Non-Hodgkin |
2014-04-01 |
2019-03-19 |
Treatments |
|
| JapicCTI-111478 | P1 |
Completed |
Multiple Myeloma|Chronic Lymphoid Leukemia|Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Chronic Myeloid Leukemia|Lymphoma, Non-Hodgkin |
2013-12-31 |
|||
| NCT01184807 | P1 |
Completed |
Gastrointestinal Stromal Tumors|Small Cell Lung Cancer|Melanoma|Gastrointestinal Cancer|Non-Small-Cell Lung Cancer|Acute Respiratory Distress Syndrome |
2013-06-01 |
2019-03-19 |
||
| NCT01423903 | P1 |
Completed |
Mouth Cancer |
2013-04-01 |
2019-03-19 |
Treatments |
Recent News Events
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