Drug Search Results

Nelivaptan

Alternative Names: nelivaptan, ssr149415
Latest Update: 2025-04-16
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: V1b Antagonist

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Sanofi
Company Location: PARIS I0 75008
Company CEO: Paul Hudson
Additional Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Nelivaptan

Countries in Clinic: Bulgaria, Estonia, Germany, Lithuania, Poland, Slovakia, Spain

Active Clinical Trial Count: 2

Highest Development Phases

Phase 2: Depressive Disorder, Major

Trial	Phase	Trial Status	Disease	Primary Completion Date	Probability of Success
BH-200-03	P2	Completed	Depressive Disorder, Major	2025-04-08
OLIVE	P2	Active, not recruiting	Depressive Disorder, Major	2024-08-14

Recent News Events

Date	Type	Title
01/01/2024	PubMed	The HPA Axis as Target for Depression.
10/03/2022	PubMed	Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review.
01/25/2022	News Article	HMNC Brain Health Expands International Patent Portfolio with Two Stress-axis Related Substances for Major Depressive Disorder
01/23/2022	PubMed	Spinal neurochemical mechanisms of acute stress-induced visceral hypersensitivity in healthy rats.

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