Product Description
NA-931, based on the mechanism of action of four receptor agonists—IGF-1, GLP-1, GIP, and Glucagon—and their roles to facilitate weight loss without many of the adverse events associated with current obesity drugs. NA-931 is in Phase 2B clinical trials. NA-931 not only significantly reduces body fat but also preserves muscle mass. Furthermore, NA-931 exhibits a notable reduction in adverse events commonly associated with existing treatments. In the quadruple mechanism of action of NA-931, Insulin-like Growth Factor 1 (IGF-1) plays a pivotal role in fuel metabolism and regulation of body composition. Additionally, IGF-1 in conjunction with GLP‐1, and GIP have been shown to be effective for weight loss in non-diabetic patients with obesity when given as adjunctive therapy to diet and exercise. IGF-1 also contributes to modulating glucagon secretion by inhibiting the ability of low glucose concentration to stimulate glucagon expression and secretion. (Sourced from: https://www.biomedind.com/NA-931.html)
Mechanisms of Action: GLP-1 Agonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Biomed Industries, Inc.
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, New Zealand, United States
Active Clinical Trial Count: 3
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Body Weight Changes|Obesity|Overweight|Weight Loss
Phase 1: Type 2 Diabetes
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT06615700 |
T2DM | P1 |
Completed |
Obesity|Overweight|Type 2 Diabetes |
2024-08-12 |
2024-09-28 |
Primary Endpoints|Treatments |
|
NCT06732245 |
NA-931-200 | P2 |
Not yet recruiting |
Obesity|Overweight |
2026-08-15 |
50% |
2024-12-14 |
|
NCT06564753 |
NA-931-100 | P2 |
Completed |
Body Weight Changes|Weight Loss|Obesity |
2025-02-27 |
37% |
2025-05-24 |
Patient Enrollment|Primary Completion Date|Primary Endpoints|Start Date|Study Completion Date|Treatments|Trial Status |
Recent News Events
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