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MK-7145

Alternative Names: mk-7145, mk7145, mk 7145
Latest Update: 2018-09-21
Latest Update Note: Clinical Trial Update

Product Description

an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure (Sourced from: https://pubs.acs.org/doi/abs/10.1021/acsmedchemlett.6b00122)

Mechanisms of Action: ROMK Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for MK-7145

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Kidney Diseases|Heart Failure|Hypertension

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
MK-7145-011

P1

Terminated

Heart Failure|Kidney Diseases

2014-12-17

MK-7145-018

P1

Withdrawn

Kidney Diseases

2013-12-01

MK-7145-009

P1

Completed

Hypertension

2011-12-19

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