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MK-2048

Alternative Names: mk-2048, mk2048, mk 2048
Clinical Status: Inactive
Latest Update: 2022-11-07
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: INST Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Vaginal

FDA Designation: *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Hillier, Sharon, PhD
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Recent & Upcoming Milestones

Highest Development Phases

Phase 1: Other|HIV Infections

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

Latest Trial Update Date

Data Updated
FAME103

P1

Completed

Other

2022-02-25

2022-11-08

Primary Endpoints|Study Completion Date
MTN-027

P1

Completed

HIV Infections

2016-03-01

2019-03-20

Treatments

Recent News Events

Date

Type

Title

03/16/2022

PubMed

 Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention.

05/12/2020

PubMed

 Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1-infected cells.

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