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Lisinopril

Alternative Names: lisinopril, zestril, diroton, prinivil, qbrelis, lisinoril, zestoretic, prinzide
Latest Update: 2024-06-22
Latest Update Note: Clinical Trial Update

Product Description

Lisinopril is used alone or together with other medicines to treat high blood pressure (hypertension).Lisinopril works by blocking a substance in the body that causes the blood vessels to tighten. As a result, lisinopril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. (Sourced from: https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/side-effects/drg-20069129?p=1)

Mechanisms of Action: ACE Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Indonesia | Ireland | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: Heart Failure | Heart Failure, Acute | Myocardial Infarction | Hypertension

Known Adverse Events: Heart Failure | Heart Failure, Acute | Myocardial Infarction | Hypertension | Hypotension | Acute Pain | Chest Pain | Dizziness | Headache | Pain Unspecified

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Lisinopril

Countries in Clinic: Australia, Belgium, Canada, China, Colombia, Croatia, Czech Republic, France, Germany, Greece, Hungary, India, Ireland, Italy, Japan, Nepal, Netherlands, New Zealand, Nigeria, Pakistan, Poland, Portugal, Romania, Russia, Saudi Arabia, Spain, United Kingdom, United States

Active Clinical Trial Count: 8

Highest Development Phases

Phase 3: COVID-19|Hypertension|IgA Nephropathy|Influenza, Human|Kidney Diseases|Pneumonia

Phase 2: Acquired Immunodeficiency Syndrome|Albuminuria|Deficiency Diseases|HIV Infections

Phase 1: Healthy Volunteers

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

WA43966

P3

Recruiting

IgA Nephropathy

2030-09-30

REMAP-CAP

P3

Recruiting

Pneumonia|Influenza, Human|COVID-19

2026-02-01

Vanderbilt_University MC

P2

Suspended

Kidney Diseases|Albuminuria|HIV Infections|Acquired Immunodeficiency Syndrome|Deficiency Diseases

2025-02-01

LZNP-2020-CPI-FRMT

P1

Completed

Healthy Volunteers

2021-11-06

27%

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