Contact Us
Drug Search Results
More Filters [+]

J2H-1702

Alternative Names: J2H-1702, J2H 1702, J2H1702
Latest Update: 2024-03-07
Latest Update Note: Clinical Trial Update

Product Description

J2H-1702 is a novel 11β-HSD1 inhibitor, and the inhibition of 11β-HSD1 has been shown to improve insulin sensitivity, reduce inflammation, and prevent the development of nonalcoholic steatohepatitis (NASH) in preclinical models. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/37743843/)

Mechanisms of Action: 11b-HSD Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: J2H Biotech
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for J2H-1702

Countries in Clinic: Korea

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Fatty Liver, Alcoholic|Hepatitis, Alcoholic|Non-alcoholic Steatohepatitis

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
JH-221-201

P2

Recruiting

Fatty Liver, Alcoholic|Non-alcoholic Steatohepatitis|Hepatitis, Alcoholic

2025-01-01

Recent News Events

Date

Type

Title

12/01/2023

PubMed

 First in human randomised trial of J2H-1702: A novel 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for non-alcoholic steatohepatitis treatment.

11/29/2022

PubMed

 Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH.

Did PRYZM just deliver the data you were looking for?
Did you try our Excel download too?

Now that you’ve used PRYZM, we hope you’re able to see for yourself that it was designed and developed by people who actually use this data for a living. By applying next-generation technology for aggregating and curating this info across multiple key sources PRYZM delivering the latest information at your fingertips just the way you need it and with industry leading speed and cost effectiveness.

Our subscribers enjoy unlimited searches and receive this data on their own secure instance so they can overlay any additional internal/proprietary data on top of the search results and blend that data with real-time industry intel from PRYZM. Discover how you can continue to uncover the competitive landscape and drive strategy.

Suggestions