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Indometacin

Alternative Names: indometacin, indomethacin, indocin, indometacine, mobilan, indomethacin extended-release, Indocid, tivorbex, indo-lemmon, GSK4381406, GSK 4381406, GSK-4381406
Latest Update: 2024-12-18
Latest Update Note: Clinical Trial Update

Product Description

Indomethacin is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Indomethacin is also used to treat pain in the shoulder caused by bursitis (inflammation of a fluid-filled sac in the shoulder joint) and tendinitis (inflammation of the tissue that connects muscle to bone). Indomethacin immediate-release capsules and suspension (liquid) are also used to treat acute gouty arthritis (attacks of severe joint pain and swelling caused by a build-up of certain substances in the joints). Indomethacin is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation. (Sourced from: https://medlineplus.gov/druginfo/meds/a681027.html)

Mechanisms of Action: AKR1C3 Inhibitor,COX Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral,Rectal

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Ireland | Israel | Italy | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: Acute Pain | Chronic Pain | Pain Unspecified | Arthritis, Rheumatoid | Spondylitis, Ankylosing | Spondylitis | Arthritis | Arthritis, Gouty | Bursitis | Gout | Osteoarthritis | Shoulder Pain | Acute Pain | Chronic Pain | Pain Unspecified | Arthritis, Rheumatoid | Spondylitis, Ankylosing | Spondylitis | Arthritis | Arthritis, Gouty | Bursitis | Gout | Osteoarthritis | Shoulder Pain | Acute Pain | Pain Unspecified

Known Adverse Events: Dizziness | Headache | Dyspepsia | Abdominal Pain | Pain Unspecified | Syncope | Hyperhidrosis | Pruritus | Constipation | Diarrhea | Edema

Company: Iroko
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Indometacin

Countries in Clinic: China, Hong Kong, Thailand

Active Clinical Trial Count: 4

Highest Development Phases

Phase 3: Obstetric Labor, Premature|Osteoarthritis|Pancreatitis|Shoulder Pain|Tennis Elbow|Tenosynovitis

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

StentvsNSAID

P3

Recruiting

Pancreatitis

2025-12-31

TOCOMED

P3

Not yet recruiting

Obstetric Labor, Premature

2024-04-01

CTR20202362

P1

Not yet recruiting

Tennis Elbow|Tenosynovitis|Osteoarthritis|Shoulder Pain

None

CTR20222093

P3

Not yet recruiting

Shoulder Pain|Tennis Elbow|Tenosynovitis|Osteoarthritis

None

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