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Floxuridine

Alternative Names: floxuridine, fluorodeoxyuridine, fudr
Latest Update: 2024-08-06
Latest Update Note: Clinical Trial Update

Product Description

Floxuridine (FUDR) is a pyrimidine analogue used as an antineoplastic agent, usually as a continuous hepatic arterial infusion to treat hepatic metastases from colon cancer. (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Floxuridine)

Mechanisms of Action: DNA Synthesis Inhibitor,TS Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous,Oral,Subcutaneous

FDA Designation: None *

Approval Status: Approved

Approved Countries: Italy | United States

Approved Indications: None

Known Adverse Events: None

Company: Jazz
Company Location: DUBLIN L2 4
Company CEO: Bruce C. Cozadd
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Floxuridine

Countries in Clinic: China, United States

Active Clinical Trial Count: 2

Highest Development Phases

Phase 2: Oncology Solid Tumor Unspecified

Phase 1: Colorectal Cancer

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
LY01616/CT-CHN-101

P2

Enrolling by invitation

Oncology Solid Tumor Unspecified

2024-08-31

57%
NCT00695201

P1

Completed

Colorectal Cancer

2021-06-28

Recent News Events

Date

Type

Title

08/05/2024

News Article

 Sirtex Medical Launches SIR-Spheres® FLEXdose SELECT Delivery Program to Enable More Selective Y-90 Treatment Plans

10/26/2022

News Article

 NuCana Presents Positive Data on NUC-3373 at the 34th EORTC-NCI-AACR Annual Meeting 2022

09/15/2022

News Article

 Sirtex Medical secures positive approval of SIR-Spheres® Y-90 resin microspheres for HCC treatment in Brazil

09/15/2022

News Article

 Sirtex Medical secures positive approval of SIR-Spheres® Y-90 resin microspheres for HCC treatment in Brazil

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