Product Description
Eribulin injection is used to treat metastatic (cancer that has already spread to other parts of the body) breast cancer in patients who have already received other types of cancer medicines. Eribulin injection is also used to treat metastatic liposarcoma or liposarcoma that cannot be removed with surgery in patients who have received other types of cancer medicines.
Mechanisms of Action: Tubulin Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous
FDA Designation: *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Belgium | Bosnia | Brazil | Canada | Chile | Colombia | Croatia | Cyprus | Czech | Denmark | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Mexico | Netherlands | Norway | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sweden | Switzerland | Taiwan | Thailand | United Arab Emirates | United Kingdom | United States | Vietnam
Approved Indications: None
Known Adverse Events: None
Company: Eisai
Company Location:
Company Founding Year: 1941
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, Canada, China, France, Germany, Israel, Italy, Japan, South Korea, Spain, Taiwan, United Kingdom, United States
Active Clinical Trial Count: 26
Recent & Upcoming Milestones
Highest Development Phases
Phase 3: Breast Cancer|Male Breast Cancer
Phase 2: Alopecia|Brain Cancer|Carcinosarcoma|Epithelioid Hemangioendothelioma|Esophageal Cancer|Gastrointestinal Cancer|Hemangiopericytoma|Hemangiosarcoma|Histiocytoma, Malignant Fibrous|Leiomyosarcoma|Liposarcoma|Liver Cancer|Mixed Tumor, Mullerian|Oncology Solid Tumor Unspecified|Ovarian Cancer|Small Cell Lung Cancer|Solitary Fibrous Tumors|Triple Negative Breast Cancer
Phase 1: Adenoid Cystic Carcinoma|Esophageal Cyst|Lymphoma|Peritoneal Cancer
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT06957431 |
NCT06957431 | P1 |
Recruiting |
Liposarcoma|Leiomyosarcoma |
2028-11-30 |
50% |
2025-10-28 |
Primary Completion Date|Primary Endpoints|Start Date|Study Completion Date|Treatments|Trial Status |
NCT03361436 |
STUDY00017190 | P1 |
Active, not recruiting |
Peritoneal Cancer|Liposarcoma |
2023-02-14 |
12% |
2023-09-15 |
|
2016-001894-34 |
BOLD 113 | P1 |
Active, not recruiting |
Lymphoma |
2020-03-02 |
2025-06-29 |
Primary Completion Date|Start Date|Study Completion Date|Treatments|Trial Status |
|
NCT03207672 |
E7389-J081-114 | P1 |
Active, not recruiting |
Breast Cancer|Esophageal Cancer|Esophageal Cyst|Small Cell Lung Cancer|Gastrointestinal Cancer|Adenoid Cystic Carcinoma |
2018-07-19 |
50% |
2024-03-02 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments |
2025-521966-91-00 |
PHP-MBC-202 | P2 |
Not yet recruiting |
Liver Cancer|Breast Cancer |
2028-12-26 |
|||
NCT04078295 |
E7389-J081-120 | P2 |
Active, not recruiting |
Oncology Solid Tumor Unspecified |
2027-03-31 |
12% |
2026-02-12 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments |
2024-512963-30-00 |
MEDOPP437 | P2 |
Recruiting |
Triple Negative Breast Cancer |
2026-12-30 |
2025-05-02 |
Treatments |
|
NCT04986579 |
NCT04986579 | P2 |
Recruiting |
Alopecia|Breast Cancer |
2026-06-01 |
75% |
2024-06-28 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments |
NCT05810870 |
SABINA | P2 |
Active, not recruiting |
Breast Cancer |
2026-04-01 |
12% |
2026-03-11 |
|
NCT05619913 |
EPOCH | P2 |
Recruiting |
Carcinosarcoma|Mixed Tumor, Mullerian|Ovarian Cancer |
2025-03-01 |
12% |
2025-02-05 |
|
NCT03840772 |
ERASING | P2 |
Completed |
Hemangiopericytoma|Solitary Fibrous Tumors |
2024-09-18 |
42% |
2024-09-21 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments|Trial Status |
NCT03899805 |
NCT03899805 | P2 |
Completed |
Histiocytoma, Malignant Fibrous|Leiomyosarcoma|Liposarcoma |
2024-07-16 |
12% |
2025-08-29 |
Primary Endpoints |
NCT03331250 |
NCT03331250 | P2 |
Active, not recruiting |
Epithelioid Hemangioendothelioma|Hemangiosarcoma |
2023-07-21 |
12% |
2024-11-09 |
Primary Completion Date|Primary Endpoints|Treatments |
2013-001269-18 |
DETECT - IV | P2 |
Completed |
Triple Negative Breast Cancer|Male Breast Cancer |
2023-06-17 |
2022-03-13 |
Treatments |
|
2018-001027-40 |
ERIBRAIN | P2 |
Completed |
Brain Cancer|Breast Cancer |
2023-03-11 |
50% |
2025-05-06 |
Treatments|Trial Status |
NCT03424005 |
Morpheus-panBC | P2 |
Recruiting |
Breast Cancer |
2030-09-30 |
12% |
2025-11-29 |
|
NCT05458674 |
02AB21-TucErBit | P2 |
Recruiting |
Breast Cancer |
2027-06-01 |
12% |
2025-01-14 |
Primary Endpoints |
2022-001398-30 |
MEN1611 IN METAPLASIC BREAST CANCER | P2 |
Active, not recruiting |
Breast Cancer |
2026-04-20 |
12% |
||
2020-004909-32 |
2020-004909-32 | P2 |
Completed |
Breast Cancer |
2024-10-01 |
2025-05-06 |
Primary Completion Date|Study Completion Date|Treatments|Trial Status |
|
2017-004652-35 |
Second line ERIbulin followed by CApecitabine or the reverse sequence in HER2-negative Metastatic Br | P2 |
Completed |
Breast Cancer |
2024-08-30 |
2025-05-06 |
||
JapicCTI-194960 |
JapicCTI-194960 | P2 |
Active |
Small Cell Lung Cancer|Esophageal Cancer|Gastrointestinal Cancer |
2022-08-31 |
|||
2016-004513-27 |
KELLY study (KEytruda and EribuLin in Luminal breast cancer) | P2 |
Active, not recruiting |
Breast Cancer |
2019-08-31 |
2022-03-13 |
Treatments |
|
NCT07173751 |
ROSETTA Breast-01 | P3 |
Recruiting |
Breast Cancer |
2029-12-01 |
73% |
2025-11-15 |
|
NCT03264547 |
EMERALD | P3 |
Completed |
Breast Cancer |
2024-12-31 |
2025-09-30 |
Patient Enrollment|Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
CTR20130252 |
CTR20130252 | P3 |
Active, not recruiting |
Male Breast Cancer |
2018-09-30 |
2025-04-29 |
Patient Enrollment|Treatments |