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Emixustat

Alternative Names: emixustat, acu-4429
Latest Update: 2024-05-30
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: RPE65 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: Orphan Drug - Stargardt Disease *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Kubota Vision
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Geographic Atrophy|Macular Degeneration|Stargardt Disease

Phase 2: Macular Degeneration|Geographic Atrophy|Stargardt Disease|Anetoderma|Diabetic Retinopathy

Phase 1: Healthy Volunteers|Geographic Atrophy|Macular Degeneration

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
The SeaSTAR Study (Safety and efficacy of EmixustAt in STARgardt disease)

P3

Unknown status

Stargardt Disease

2022-11-18

SeaSTAR

P3

Completed

Macular Degeneration|Stargardt Disease

2022-06-13

NCT02753400

P2

Completed

Diabetic Retinopathy

2017-11-01

NCT03033108

P2

Completed

Anetoderma|Stargardt Disease|Macular Degeneration

2017-11-01

Recent News Events

Date

Type

Title

10/04/2023

News Article

 Smart Health Watches Market to Observe Prominent USD 185.63 Billion Growth by 2029

10/04/2023

News Article

 Radiology Information Systems (RIS) Market to Notice Prominent USD 1,782.5 Million Growth by 2029

09/27/2023

PubMed

 Updates on Emerging Interventions for Autosomal Recessive ABCA4-Associated Stargardt Disease.

07/01/2023

PubMed

 Computational attributes of protein kinase-C gamma C2-domain & virtual screening for small molecules: elucidation from meta-dynamics simulations & free-energy calculations.

06/22/2023

PubMed

 Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif.

05/15/2023

News Article

 ABCA4 Retinopathy Therapeutics Market Will Register a CAGR of 18.6% from 2023 to 2031, says Growth Plus Reports

07/27/2022

News Article

 Kubota Vision Announces Database Lock for Phase 3 Clinical Trial of Emixustat in Patients with Stargardt Disease and Expected Release of Top-Line Results in August 2022

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