Product Description
Cycloserine is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents. Cycloserine is appears to have little or no hepatotoxic potential, but it is usually used in combination with agents that are known to be hepatotoxic, and its role in the reported cases of liver injury with combination therapy cannot always be excluded. (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Cycloserine)
Mechanisms of Action: L-Alanine Racemase Inhibitor, D-Alanine Ligase Inhibitor, Cell Wall Synthesis Inhibitor, NMDA Agonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: *
Approval Status: Approved
Approved Countries: Australia | Canada | Chile | Colombia | Dominican Republic | Greece | Hong Kong | India | Ireland | Korea | Lithuania | Malaysia | Malta | Mexico | New Zealand | Pakistan | Peru | Philippines | Romania | Russia | Slovenia | South Africa | Sri Lanka | Taiwan | Thailand | Turkey | Ukraine | United Kingdom | United States | Uruguay | Vietnam
Approved Indications: None
Known Adverse Events: None
Company: Zhejiang University
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count: 1
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Depressive Disorder, Major
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|
| NCT03401164 | P2 |
Not yet recruiting |
Depressive Disorder, Major |
2019-12-01 |
2019-03-22 |
Treatments |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
08/26/2025 |
News Article |
NeuroStim TMS Pioneers Accelerated One-Day TMS™ for Depression |
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06/24/2025 |
News Article |
IBN Initiates Coverage of NRx Pharmaceuticals Inc. |
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12/18/2023 |
News Article |
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12/11/2023 |
News Article |
NRx Pharmaceuticals to Participate in LifeSci Corporate Access Event |