Ozmosi | Cotinine Drug Profile
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Cotinine

Alternative Names: cotinine
Clinical Status: Inactive
Latest Update: 2025-09-12
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: nAChR Binder

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Inhalant

FDA Designation: *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: National Institute on Drug Abuse (NIDA)
Company Location:
Company Founding Year: None
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Recent & Upcoming Milestones

Highest Development Phases

Phase 4: Acute Pain|Chronic Pain

Phase 2: Tobacco Use Disorder

Trial ID

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

Latest Trial Update Date

Data Updated

NCT07003282

First Breath

N/A

Recruiting

Pregnancy Outcomes|Tobacco Use Disorder

2025-10-30

2025-09-13

Primary Endpoints

NCT06645340

PRE_Smoking

N/A

Completed

Hypertension, Pregnancy-Induced|Pregnancy Outcomes|Pre-Eclampsia

2022-09-30

2024-10-24

NCT02897401

CANICE

N/A

Unknown status

Tobacco Use Disorder|Carcinogenesis

2017-11-01

2024-12-19

Primary Endpoints|Treatments

NCT03062709

NCT03062709

N/A

Completed

Tobacco Use Disorder|Bronchiolitis|Pneumonia|Asthma|Bronchopulmonary Dysplasia|Smoking Cessation

2017-03-30

2021-04-27

Primary Endpoints|Treatments

NCT00217893

R01HL066307

N/A

Completed

Asthma

2008-01-01

2019-03-21

Treatments

ACTRN12612000399897

ENtiCe

N/A

Not yet recruiting

Pregnancy Outcomes|Tobacco Use Disorder

None

2026-02-15

Treatments

NCT01828502

SCUSF 1201

P2

Withdrawn

Tobacco Use Disorder

2016-06-01

2019-03-19

Treatments

NCT00000296

NIDA-09259-13

P2

Completed

Tobacco Use Disorder

None

2019-03-21

Treatments

NCT00000288

NIDA-09259-5

P2

Completed

Tobacco Use Disorder

None

2019-03-21

Treatments

NCT00000284

NIDA-09259-1

P2

Completed

Tobacco Use Disorder

None

2019-03-21

Treatments

NCT04274673

NCT04274673

P4

Unknown status

Acute Pain|Chronic Pain

2020-05-13

2022-02-02

Primary Endpoints|Treatments|Trial Status