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Collagenase clostridium histolyticum

Alternative Names: collagenase clostridium histolyticum, Xiaflex, qwo
Latest Update: 2024-12-16
Latest Update Note: News Article

Product Description

Collagenase clostridium histolyticum injection is used to treat Dupuytren's contracture with a palpable cord. It is also used to treat Peyronie's disease with a palpable plaque and curvature deformity in men. (Sourced from: https://www.mayoclinic.org/drugs-supplements/collagenase-clostridium-histolyticum-injection-route/description/drg-20073911)

Mechanisms of Action: MMP Inhibitor

Novel Mechanism: No

Modality: Nondrug

Route of Administration: Oral,Subcutaneous

FDA Designation: None *

Approval Status: Approved

Approved Countries: Brazil | Bulgaria | Canada | European Medicines Agency | Greece | Hungary | Ireland | Lithuania | Malaysia | Poland | Portugal | Slovakia | Slovenia | Sweden

Approved Indications: Contracture | Dupuytren Contracture | Cellulite

Known Adverse Events: Pain Unspecified | Contracture | Dupuytren Contracture | Edema | Erythema | Pruritus

Company: Endo
Company Location: DUBLIN 4 L2 00000
Company CEO: Blaise Coleman
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Collagenase clostridium histolyticum

Countries in Clinic: United States

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Cellulite|Edema

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
APHRODITE

P2

Completed

Cellulite|Edema

2023-01-03

24%

Recent News Events

Date

Type

Title

12/16/2024

News Article

 Endo Announces Publication of Peyronie's Disease Self-Assessment Screening App Article in Peer-Reviewed Translational Andrology and Urology

11/20/2024

News Article

 John Elway Teams Up with Endo to Share Update on Dupuytren's Contracture and Treatment with XIAFLEX® (collagenase clostridium histolyticum)

10/25/2024

News Article

 Endo Announces Peyronie's Disease Presentation at the SurgeWest Annual Meeting of the Western Section of the American Urological Association

10/18/2024

News Article

 Endo Presents Data at the American Society of Podiatric Surgeons (ASPS) Annual Surgical Conference

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