Product Description
COLLAGENASE (kohl LAH jen ace) is an enzyme that breaks down collagen in damaged tissue and helps healthy tissue to grow. It may help wounds heal faster. (Sourced from: https://my.clevelandclinic.org/health/drugs/18678-collagenase-ointment)
Mechanisms of Action: MMP Inhibitor
Novel Mechanism: No
Modality: Peptide/Protein
Route of Administration: Topical, Injection
FDA Designation: *
Approval Status: Approved
Approved Countries: Argentina | Austria | Belgium | Brazil | Bulgaria | Canada | Chile | Colombia | Czech | Dominican Republic | Ecuador | Egypt | France | Germany | Hong Kong | Hungary | India | Ireland | Italy | Japan | Luxembourg | Malaysia | Mexico | Netherlands | New Zealand | Peru | Poland | Portugal | Russia | Slovakia | Slovenia | Spain | Switzerland | Taiwan | Thailand | Turkey | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela
Approved Indications: None
Known Adverse Events: None
Company: Healthpoint
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, Austria, Germany, Italy, Sweden
Active Clinical Trial Count: 4
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Dupuytren Contracture
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
2023-507332-20-00 |
RR37_23_01 | P2 |
Recruiting |
Dupuytren Contracture |
2026-07-31 |
2025-05-02 |
Treatments |
|
2023-509621-45-00 |
RRE8_23_01 | P2 |
Recruiting |
Unknown |
2027-06-03 |
2025-05-02 |
Treatments |
|
ACTRN12624000664549 |
ACTRN12624000664549 | P2 |
Recruiting |
Dupuytren Contracture |
2025-05-17 |
2024-09-07 |
Patient Enrollment|Start Date|Treatments|Trial Status |
|
2022-000666-17 |
Vibrio alginolyticus collagenase Phase II | P2 |
Completed |
Dupuytren Contracture |
2023-11-10 |
2025-05-06 |
Primary Completion Date|Start Date|Study Completion Date|Treatments|Trial Status |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
10/15/2025 |
News Article |
Endo Announces Peyronie's Disease Presentation at the North Central Section of the American Urological Association |
|
10/09/2025 |
News Article |
Endo Announces Nine New and Modified Presentations at the Sexual Medicine Society of North America (SMSNA) Annual Meeting |
|
09/10/2025 |
News Article |
Endo Presents Plantar Fibromatosis and Plantar Fasciitis Data at the American Orthopaedic Foot & Ankle Society Annual Meeting |
|
09/02/2025 |
News Article |
First National Hand Health Month Empowers People to Live a Hands-On Life |