Product Description
COLLAGENASE (kohl LAH jen ace) is an enzyme that breaks down collagen in damaged tissue and helps healthy tissue to grow. It may help wounds heal faster. (Sourced from: https://my.clevelandclinic.org/health/drugs/18678-collagenase-ointment)
Mechanisms of Action: MMP Inhibitor
Novel Mechanism: No
Modality: Peptide/Protein
Route of Administration: Topical, Injection
FDA Designation: *
Approval Status: Approved
Approved Countries: Argentina | Austria | Belgium | Brazil | Bulgaria | Canada | Chile | Colombia | Czech | Dominican Republic | Ecuador | Egypt | France | Germany | Hong Kong | Hungary | India | Ireland | Italy | Japan | Luxembourg | Malaysia | Mexico | Netherlands | New Zealand | Peru | Poland | Portugal | Russia | Slovakia | Slovenia | Spain | Switzerland | Taiwan | Thailand | Turkey | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela
Approved Indications: None
Known Adverse Events: None
Company: Healthpoint
Company Location:
Company Founding Year: None
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Austria, China, Germany, Italy, Sweden
Active Clinical Trial Count: 4
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Diabetic Foot|Dupuytren Contracture
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
2023-507332-20-00 |
RR37_23_01 | P2 |
Recruiting |
Dupuytren Contracture |
2026-07-31 |
2025-05-02 |
Treatments |
|
2023-509621-45-00 |
RRE8_23_01 | P2 |
Recruiting |
Unknown |
2027-06-03 |
2025-05-02 |
Treatments |
|
2022-000666-17 |
Vibrio alginolyticus collagenase Phase II | P2 |
Completed |
Dupuytren Contracture |
2023-11-10 |
2025-05-06 |
Primary Completion Date|Start Date|Study Completion Date|Treatments|Trial Status |
|
CTR20251247 |
CTR20251247 | P2 |
Active, not recruiting |
Diabetic Foot |
None |
2026-01-18 |
Patient Enrollment|Treatments|Trial Status |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
02/16/2026 |
News Article |
Keenova Announces New Manuscript on Plantar Fibromatosis Treatment Patterns in Peer-Reviewed Journal of Foot and Ankle Surgery |
|
02/10/2026 |
News Article |
DEVONIAN REPORTS POSITIVE RESULTS IN PULMONARY FIBROSIS STUDY |
|
01/21/2026 |
News Article |
Keenova Marks 100K Peyronie's Disease Patients--a Major Milestone for an Often-Stigmatized Men's Health Condition |
|
01/14/2026 |
News Article |
Keenova to Demonstrate Live Dupuytren's Contracture Treatment Procedure During American Association for Hand Surgery Meeting |