Product Description
CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody that recognizes a unique epitope on CD38. It was engineered to have strong activity against CD38 malignant cells and to reduce certain safety issues observed with existing treatments. Preclinical data of CID-103 demonstrates enhanced activity against a broad array of malignancies which express CD38 and demonstrates a better preclinical safety profile when compared to other CD38 mAbs. These attributes offer the potential for accelerated development and regulatory review, including rapid advancement into earlier lines of therapy. (Sourced from: https://www.casipharmaceuticals.com/product-pipeline/anti-cd38-monoclonal-antibody)
Mechanisms of Action: CD38 Inhibitor
Novel Mechanism: No
Modality: Antibody
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: CASI
Company Location: ROCKVILLE MD 20850
Company CEO: Wei-Wu He
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: France, United Kingdom
Active Clinical Trial Count: 1
Highest Development Phases
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| CASI-CID-103-101 | P1 |
Active, not recruiting |
Unknown |
2023-09-01 |
34% |