Product Description
Buspirone is used to treat anxiety disorders or in the short-term treatment of symptoms of anxiety. Buspirone is in a class of medications called anxiolytics. It works by changing the amounts of certain natural substances in the brain. (Sourced from: https://medlineplus.gov/druginfo/meds/a688005.html)
Mechanisms of Action: 5-HT1A Agonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: *
Approval Status: Approved
Approved Countries: Bangladesh | Brazil | Canada | Chile | China | Colombia | Czech | Denmark | Dominican Republic | Egypt | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Indonesia | Ireland | Israel | Italy | Korea | Latvia | Lithuania | Malta | Netherlands | New Zealand | Norway | Pakistan | Peru | Poland | Portugal | Romania | Russia | Slovakia | Slovenia | South Africa | Sri Lanka | Sweden | Taiwan | Turkey | Ukraine | United Kingdom | United States | Venezuela
Approved Indications: None
Known Adverse Events: None
Company: Emotional Brain
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: China
Active Clinical Trial Count: 2
Recent & Upcoming Milestones
Highest Development Phases
Phase 3: Generalized anxiety disorder|Myocardial Infarction
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT06243614 |
BGFN-2022-01 | P3 |
Recruiting |
Generalized anxiety disorder |
2026-06-30 |
15% |
2024-02-07 |
|
2016-004501-14 |
COOL AMI EU PIVOTAL TRIAL | P3 |
Active, not recruiting |
Myocardial Infarction |
None |
2025-07-05 |
Treatments |
Recent News Events
Date |
Type |
Title |
|---|---|---|
|
04/09/2025 |
News Article |
Cingulate Receives $3 Million Grant from Private Foundation to Accelerate Development of Anxiety Asset CTx-2103 (buspirone) |
|
03/19/2024 |
News Article |
Cingulate to Participate in Benzinga All Live Access Event |
|
03/06/2024 |
News Article |
Cingulate to Attend DCAT Week 2024 in New York City |
|
02/21/2024 |
News Article |
Enveric Biosciences Unveils Library of Preclinical Compounds Across Multiple Distinct Molecule Classes Targeting Mental Health Disorders |