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BMS-394136

Alternative Names: bms-394136, bms394136, bms 394136
Latest Update: 2008-08-20
Latest Update Note: Clinical Trial Update

Product Description

Bristol-Myers Squibb developed BMS-394136, as a selective IKur inhibitor for the treatment of arrhythmias. IKur is a repolarizing K+ current encoded by the KCNA5 gene and is expressed predominantly in the atrium of human. IKur is a potential atrial-selective target for the treatment of atrial fibrillation. Atrial selectivity and safety of BMS-394136 were studied in phase I clinical trial in patients with heart diseases. (Sourced from: https://drugs.ncats.io/drug/M694U7167K)

Mechanisms of Action: IKur Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Bristol-Myers Squibb
Company Location: NEW YORK NY 10016
Company CEO: Giovanni Caforio
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for BMS-394136

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Other

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CV175-003

P1

Completed

Other

None

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