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Barusiban

Alternative Names: barusiban, fe-200440, fe200440, fe 200440
Latest Update: 2021-12-01
Latest Update Note: PubMed Publication

Product Description

Barusiban is an oxytocin antagonist under development for potential use as tocolytic in preterm-labor patients. Barusiban (FE 200440) is a peptide oxytocin antagonist for potential future use as a tocolytic drug in preterm-labor patients, being slightly smaller than atosiban. (Sourced from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313255/)

Mechanisms of Action: OXTR Antagonist

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Ferring
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Barusiban

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Infertility|Pregnancy Outcomes|Other|Infertility, Male|Infertility, Female|Obstetric Labor, Premature

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
BASIC

P2

Completed

Infertility, Male|Infertility, Female

2014-10-08

BASIC

P2

Completed

Infertility

2014-10-01

EFFORT

P2

Completed

Pregnancy Outcomes

2010-12-02

EFFORT

P2

Completed

Other

2010-05-01

Recent News Events

Date

Type

Title

12/01/2021

PubMed

 Is oxytocin receptor antagonist administration around embryo transfer associated with IVF treatment success? A systematic review and meta-analysis.

09/01/2021

PubMed

 Oxytocin antagonists for assisted reproduction.

10/15/2020

News Article

 Ferring Pharmaceuticals to Share New Reproductive Medicine Data at ASRM 2020 Scientific Congress & Expo

06/23/2020

PubMed

 Barusiban, a selective oxytocin receptor antagonist: placental transfer in rabbit, monkey, and human.

10/14/2019

News Article

 Ferring Pharmaceuticals to Present New Fertility Data at ASRM 2019 Scientific Congress & Expo

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