Product Description
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents. (Sourced from: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/amonafide)
Mechanisms of Action: TOP2 Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Antisoma Research
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Acute Myeloid Leukemia
Phase 2: Acute Myeloid Leukemia|Prostate Cancer|Breast Cancer
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| ACCEDE | P3 |
Terminated |
Acute Myeloid Leukemia |
2011-01-31 |
|
| AS1413-C-101 | P2 |
Unknown status |
Acute Myeloid Leukemia |
2010-09-01 |
|
| NCT00715637 | P3 |
Unknown status |
Acute Myeloid Leukemia |
2010-06-01 |
|
| AIPC | P2 |
Completed |
Prostate Cancer |
2005-12-01 |