Product Description
Alprostadil is a medication used in the management and treatment of erectile dysfunction in males and for temporary patency of ductus arteriosus in newborns with congenital heart diseases before surgical intervention. It is in the prostaglandin analog class of medications. (Sourced from: https://www.ncbi.nlm.nih.gov/books/NBK542217/)
Mechanisms of Action: EP1 Agonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Belgium | Brazil | Bulgaria | Canada | Chile | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Poland | Portugal | Romania | Russia | Saudi Arabia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela
Approved Indications: None
Known Adverse Events: None
Company: CSPC
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: China
Active Clinical Trial Count: 3
Highest Development Phases
Phase 2: Acute Kidney Injury|Optic Neuropathy, Ischemic
Phase 1: Angina Pectoris|Atherosclerosis|Chronic Pain|Ductus Arteriosus, Patent|Heart Failure, Chronic|Microvascular Angina|Myocardial Infarction|Retinal Vein Occlusion|Thrombosis
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| PG-NAION | P2 |
Active, not recruiting |
Optic Neuropathy, Ischemic |
2020-05-18 |
|
| CTR20132242 | P1 |
Recruiting |
Chronic Pain|Microvascular Angina|Heart Failure, Chronic|Angina Pectoris|Atherosclerosis|Ductus Arteriosus, Patent|Thrombosis|Retinal Vein Occlusion|Myocardial Infarction |
None |
|
| CTR20221833 | P2 |
Recruiting |
Acute Kidney Injury |
None |