Drug Search Results
More Filters [+]

Allopurinol

Alternative Names: allopurinol, zyloprim, ath-008, ath 008, ath008, lopurin, aloprim, duzallo
Latest Update: 2024-10-05
Latest Update Note: Clinical Trial Update

Product Description

Allopurinol is used to treat gout, high levels of uric acid in the body caused by certain cancer medications, and kidney stones. Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is used to prevent gout attacks, not to treat them once they occur. (Sourced from: https://medlineplus.gov/druginfo/meds/a682673.html)

Mechanisms of Action: XO Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: Leukemia | Lymphoma | Oncology Solid Tumor Unspecified | Oncology Unspecified | Gout

Known Adverse Events: Kidney Diseases | Gastroesophageal Reflux | Influenza, Human

Company: AstraZeneca
Company Location: CAMBRIDGE X0 CB2 0AA
Company CEO: Pascal Soriot
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Allopurinol

Countries in Clinic: Austria, Belgium, China, Estonia, Finland, Germany, Italy, Netherlands, Norway, Poland, Portugal, Spain, Switzerland, United States, Unknown Location

Active Clinical Trial Count: 15

Highest Development Phases

Phase 3: Brain Death|Brain Injuries|Congenital Heart Defects|Gout|Hypothermia|Hypoxia-Ischemia, Brain

Phase 2: Autism Spectrum Disorder|Epilepsy|Heart Failure, Chronic|Heart Failure, Diastolic

Phase 1: Healthy Volunteers

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

CRUCIAL

P3

Recruiting

Congenital Heart Defects

2026-10-31

ALBINO

P3

Recruiting

Hypoxia-Ischemia, Brain|Brain Injuries

2026-01-31

D0120-205

P2

Recruiting

Gout

2025-07-31

EURELIA2

P3

Recruiting

Gout

2025-07-01

34%

EURELIA2

P3

Recruiting

Gout

2025-07-01

34%

Recent News Events