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Alizapride

Alternative Names: alizapride
Latest Update: 2024-06-29
Latest Update Note: Clinical Trial Update

Product Description

Dopamine D2 receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. (Sourced from: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=11141)

Mechanisms of Action: DR Antagonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Belgium | Brazil | Colombia | Dominican Republic | Egypt | France | Italy | Luxembourg | Peru | Portugal | Taiwan

Approved Indications: None

Known Adverse Events: None

Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Alizapride

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 4: Breast Cancer

Phase 2: Oncology Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
IJB-IRAES-2020

P2

Unknown Status

Oncology Unspecified

2027-06-30

GEICAM/2009-02

P4

Completed

Breast Cancer

2013-03-01

Recent News Events

Date

Type

Title

09/01/2021

PubMed

 Long term stability of an admixture of alizapride and ondansetron in 0.9% sodium chloride solution polyolefin bags stored at 53C.

03/01/2020

PubMed

 Long-term stability of an infusion containing paracetamol, alizapride, ketorolac and tramadol in glass bottles at 53C.

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