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Adenosine

Alternative Names: adenosine, adenoscan, adenocard
Latest Update: 2025-01-20
Latest Update Note: News Article

Product Description

Adenosine is a purine nucleoside base, most commonly recognized with the molecule adenosine triphosphate, or ATP, and is used thoroughly throughout the entire body in general metabolism. Adenosine’s use as a pharmacological drug works through receptors called purinergic adenosine receptors found throughout the body. Diagnostically, adenosine is one pharmaceutical agent used in a myocardial perfusion stress imaging study for its vasodilatory effects. Therapeutically, adenosine is used for its antiarrhythmic properties in supraventricular tachycardia (SVT) and can function as a diagnostic tool as well, depending on the type of SVT. (Sourced from: https://www.ncbi.nlm.nih.gov/books/NBK519049/)

Mechanisms of Action: ADORA1 Agonist,ADORA2A Agonist,ADORA2B Agonist,ADORA3 Agonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Brazil | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: Generalized anxiety disorder

Known Adverse Events: Dizziness | Headache | Flushing

Company: TRPHARM
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Adenosine

Countries in Clinic: China

Active Clinical Trial Count: 2

Highest Development Phases

Phase 3: Coronary Disease|Myocardial Ischemia

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

CTR20201171

P3

Not yet recruiting

Myocardial Ischemia

None

CTR20231854

P3

Not yet recruiting

Coronary Disease

None

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