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A2B694

Alternative Names: A2B694
Latest Update: 2024-10-04
Latest Update Note: News Article

Product Description

A2B694 is a autologous CAR-T cell candidate from A2 Bio, which acts as a MSLN activator and HLA-A*02 blocker for the treatment of Ovarian, Mesothelioma, Colorectal, Lung and Pancreatic Cancers. (Sourced from: https://www.a2bio.com/our-pipeline/)

Mechanisms of Action: Cell Therapy,HLA

Novel Mechanism: Yes

Modality: Cell Therapy

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: A2 Bio
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for A2B694

Countries in Clinic: United States

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Adenocarcinoma|Colorectal Cancer|Mesothelioma|Non-Small-Cell Lung Cancer|Ovarian Cancer|Pancreatic Cancer|Squamous Cell Carcinoma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
EVEREST-2

P2

Recruiting

Pancreatic Cancer|Non-Small-Cell Lung Cancer|Squamous Cell Carcinoma|Mesothelioma|Adenocarcinoma|Ovarian Cancer|Colorectal Cancer

2028-06-01

Recent News Events

Date

Type

Title

10/04/2024

News Article

 A2 Bio to Present Safety and Biomarker Data from EVEREST-1 Trial during 2024 Annual Meeting of the Society for Immunotherapy of Cancer

05/29/2024

News Article

 A2 Bio Highlights Progress of CAR T-Cell Clinical Programs in Three Poster Presentations during the American Society of Clinical Oncology (ASCO) 2024 Annual Meeting

05/16/2024

News Article

 A2 Bio Announces First Patient Dosed in EVEREST-2 Phase 1 Clinical Trial of Novel Mesothelin Logic-Gated CAR T

04/24/2024

News Article

 A2 Bio to Highlight Progress of CAR T Clinical Programs in Three Poster Presentations at 2024 American Society of Clinical Oncology (ASCO) Annual Meeting

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