Product Description
Furosemide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine. urosemide is used alone or in combination with other medications to treat high blood pressure. Furosemide is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease. (Sourced from: https://medlineplus.gov/druginfo/meds/a682858.html)
Mechanisms of Action: NKCC Inhibitor,TGFR Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous,Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Heart Failure | Heart Failure, Acute | Heart Failure, Chronic | Liver Failure | Liver Failure, Acute | Pulmonary Edema | Edema
Known Adverse Events: Pain Unspecified | Erythema | Edema
Company: scPharmaceuticals
Company Location: BURLINGTON MA 01803
Company CEO: John H. Tucker
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, China, Czech Republic, Germany, Spain, United States, Unknown Location
Active Clinical Trial Count: 11
Highest Development Phases
Phase 3: Heart Failure
Phase 2: Adenocarcinoma|Dyspnea|Prostate Cancer
Phase 1: Gout|Healthy Volunteers|Malaria|Type 2 Diabetes
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| STUDY00004720 | P2 |
Active, not recruiting |
Adenocarcinoma|Prostate Cancer |
2027-07-01 |
|
| INFURO_2023 | P2 |
Recruiting |
Dyspnea |
2026-01-01 |
|
| U1111-1302-1171 | P1 |
Recruiting |
Healthy Volunteers |
2024-10-16 |
|
| scP-04-001 | P1 |
Completed |
Heart Failure |
2024-06-14 |