Product Description
Baicalein is a trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. It has a role as an antioxidant, a hormone antagonist, a prostaglandin antagonist, an EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, a radical scavenger, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an anti-inflammatory agent, a plant metabolite, a ferroptosis inhibitor, an anticoronaviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an angiogenesis inhibitor, an antineoplastic agent, an EC 4.1.1.17 (ornithine decarboxylase) inhibitor, an antibacterial agent, an antifungal agent, an apoptosis inducer and a geroprotector. It is a conjugate acid of a baicalein(1-). (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Baicalein)
Mechanisms of Action: PG Antagonist,EP Inhibitor,ALOX15 Inhibitor,ALOX12 Inhibitor
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: CSPC
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description

Countries in Clinic: China
Active Clinical Trial Count: 1
Highest Development Phases
Phase 2: Influenza, Human
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
CTR20182427 | P2 |
Recruiting |
Influenza, Human |
None |