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Baicalein

Alternative Names: baicalein, sho-saiko-to
Latest Update: 2024-05-10
Latest Update Note: PubMed Publication

Product Description

Baicalein is a trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. It has a role as an antioxidant, a hormone antagonist, a prostaglandin antagonist, an EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, a radical scavenger, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an anti-inflammatory agent, a plant metabolite, a ferroptosis inhibitor, an anticoronaviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an angiogenesis inhibitor, an antineoplastic agent, an EC 4.1.1.17 (ornithine decarboxylase) inhibitor, an antibacterial agent, an antifungal agent, an apoptosis inducer and a geroprotector. It is a conjugate acid of a baicalein(1-). (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Baicalein)

Mechanisms of Action: PG Antagonist,EP Inhibitor,ALOX15 Inhibitor,ALOX12 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: CSPC
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Baicalein

Countries in Clinic: China

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Influenza, Human

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

CTR20182427

P2

Recruiting

Influenza, Human

None

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