Product Description
Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. (Sourced from: https://www.ncbi.nlm.nih.gov/gene/133)
Mechanisms of Action: No Mechanism
Novel Mechanism: No
Modality: Peptide/Protein
Route of Administration: Intravenous
FDA Designation: *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: University of Miyazaki
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: CADASIL|Colitis, Ulcerative|Dementia, Multi-Infarct|Crohn Disease
Phase 1: Healthy Volunteers|Colitis, Ulcerative|Crohn Disease
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|
| AML2220 | N/A |
Unknown status |
Acute Myeloid Leukemia |
2024-06-01 |
2024-11-02 |
Primary Endpoints |
|
| H-18020494 | N/A |
Completed |
Migraine Disorders|Headache Disorders |
2020-01-30 |
2020-03-12 |
Primary Completion Date|Primary Endpoints|Start Date|Study Completion Date|Treatments |
|
| ChiCTR-IPR-16007847 | N/A |
Not yet recruiting |
Oxidative Stress|Hypoxia|Acute Respiratory Distress Syndrome|Cardiac Output, High|Acute Lung Injury|Cardiac Output, Low|Reperfusion Injury |
2016-03-01 |
|||
| CEP1781/07 | N/A |
Withdrawn |
Heart Failure |
2010-12-01 |
2019-03-19 |
Treatments |
|
| Adults | P1 |
Completed |
Crohn Disease|Colitis, Ulcerative |
2022-12-19 |
2023-02-02 |
||
| JapicCTI-194890 | P1 |
Completed |
Healthy Volunteers |
2016-11-30 |
|||
| JapicCTI-194891 | P1 |
Completed |
Healthy Volunteers |
2016-03-31 |
|||
| AMCAD | P2 |
Completed |
CADASIL|Dementia, Multi-Infarct |
2023-01-23 |
2023-10-11 |
Primary Endpoints|Treatments |
|
| JapicCTI-183947 | P2 |
Unknown |
Crohn Disease |
2020-03-31 |
|||
| JapicCTI-205255 | P2 |
Unknown |
Colitis, Ulcerative |
2019-05-31 |