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Filociclovir

Alternative Names: filociclovir, mbx-400, mbx400
Latest Update: 2022-12-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: DNA Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Microbiotix
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Filociclovir

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Stem Cell Transplant|Cytomegalovirus Infections|Deafness|HIV Infections|Inflammation|Coronary Stenosis|Coronary Disease|Coronary Restenosis|Pneumonia|Cytomegalovirus Retinitis|Transplantation Unspecified|Myocarditis

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
HHSN272201300018I

P1

Completed

Cytomegalovirus Infections

2017-04-01

NCT01433835

P1

Completed

Coronary Stenosis|Inflammation|Cytomegalovirus Retinitis|Pneumonia|Coronary Disease|Transplantation Unspecified|Myocarditis|Deafness|HIV Infections|Coronary Restenosis|Stem Cell Transplant

2012-08-01

Recent News Events

Date

Type

Title

12/01/2022

PubMed

 Filociclovir is a potent inhibitor of human adenovirus F41.

05/19/2022

News Article

 Viral Conjunctivitis Drugs in Development Pipeline Guide 2022, by Stages, Target, MoA, RoA, Molecule Type and Key Players - ResearchAndMarkets.com

03/26/2021

PubMed

 Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model.

10/20/2020

PubMed

 Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses.

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