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YTTRIUM-90

Alternative Names: yttrium-90, yttrium (90y) clivatuzumab tetraxetan, 90y-hpam4, hpam4, immu-107, yttrium
Latest Update: 2025-04-09
Latest Update Note: Clinical Trial Update

Product Description

Yttrium-90 microspheres are radioactive particles which are increasingly being employed for treating patients with unresectable hepatocellular carcinoma (HCC).

Mechanisms of Action: CD22 Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Gilead Sciences
Company Location: FOSTER CITY CA 94404
Company CEO: Daniel P. O’Day
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for YTTRIUM-90

Countries in Clinic: China, Germany, United States

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Hepatocellular Carcinoma|Liver Cancer

Phase 2: Primary Central Nervous System Lymphoma

Phase 1: Oncology Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
NCT06902246

P2

Not yet recruiting

Hepatocellular Carcinoma

2030-06-01

NRT6003-HCC-2024

P3

Not yet recruiting

Hepatocellular Carcinoma

2027-10-01

NCI-2021-13239

P1

Recruiting

Oncology Unspecified

2026-03-31

S6371

P3

Active, not recruiting

Hepatocellular Carcinoma

2026-02-28

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