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Vesencumab

Alternative Names: vesencumab, MNRP1685A
Latest Update: 2023-11-08
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: NRP1 Inhibitor

Novel Mechanism: Yes

Modality: Antibody

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Hoffmann-La Roche
Company Location: BASEL SWITZERLAND V8
Company CEO: Severin Schwan
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Vesencumab

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
ANP4667g

P1

Completed

Oncology Solid Tumor Unspecified

2011-12-01

ANP4509g

P1

Completed

Oncology Solid Tumor Unspecified

None

Recent News Events

Date

Type

Title

11/08/2023

PubMed

 A Comprehensive Analysis of NRP1 in Malignancies Provide Therapeutic Implication for Treating Cancer Patients Infected with SARS-CoV-2.

01/25/2022

PubMed

 Neuropilin-1 is over-expressed in claudin-low breast cancer and promotes tumor progression through acquisition of stem cell characteristics and RAS/MAPK pathway activation.

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