Product Description
Valategrast (RO-0272441) is an orally available, small molecule alpha4 integrin inhibitor that was developed by Roche. It is active at alpha4beta1 and alpha4beta7 integrins. (Sourced from: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?tab=biology&ligandId=11487)
Mechanisms of Action: ITGA4-B7 Antagonist,VLA Antagonist
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: None
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
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