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Evofosfamide

Alternative Names: evofosfamide, th-302
Latest Update: 2024-05-15
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Alkylating Agent

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Molecular Templates
Company Location: AUSTIN TX 78729
Company CEO: Eric E. Poma
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Evofosfamide

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Pancreatic Cancer|Adenocarcinoma|Sarcoma

Phase 2: Sarcoma|Melanoma|Neuroendocrine Tumors|Glioblastoma|Pancreatic Cancer|Adenocarcinoma|Multiple Myeloma|Non-Small-Cell Lung Cancer|Prostate Cancer|Biliary Tract Cancer|Glioma|Astrocytoma

Phase 1: Liver Cancer|Kidney Cancer|Anorexia|Alopecia|Neuroendocrine Carcinoma|Renal Cell Carcinoma|Thrombocytopenia|Hypertension|Head and Neck Cancer|Neuroendocrine Tumors|Hypoxia|Esophageal Cancer|Anemia|Hepatocellular Carcinoma|Neutropenia|Diarrhea|Pancreatic Cancer|Gastrointestinal Stromal Tumors|Islet Cell Carcinoma|Gastrointestinal Cancer|Islet Cell Adenoma|Squamous Cell Carcinoma|Acute Myeloid Leukemia|Chronic Lymphoid Leukemia|Preleukemia|Lymphoma, B-Cell|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Melanoma|Chronic Myeloid Leukemia|Lymphocytic Chronic B-Cell Leukemia|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Myelodysplastic Syndrome|Myelofibrosis|Prostate Cancer|Acute Lymphoid Leukemia|Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

SUNINET

P2

Completed

Neuroendocrine Tumors

2020-01-10

CTRC 12-0105

P2

Completed

Glioblastoma

2019-01-04

TH-CR-417

P1

Unknown status

Squamous Cell Carcinoma|Prostate Cancer|Head and Neck Cancer|Melanoma|Pancreatic Cancer

2019-01-01

GETNE-1408

P2

Completed

Neuroendocrine Tumors|Pancreatic Cancer

2018-05-31

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