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Evofosfamide

Alternative Names: evofosfamide, th-302
Latest Update: 2024-05-15
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Alkylating Agent

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Molecular Templates
Company Location: AUSTIN TX 78729
Company CEO: Eric E. Poma
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Evofosfamide

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Adenocarcinoma|Pancreatic Cancer|Sarcoma

Phase 2: Non-Small-Cell Lung Cancer|Sarcoma|Multiple Myeloma|Glioblastoma|Neuroendocrine Tumors|Biliary Tract Cancer|Melanoma|Astrocytoma|Glioma|Pancreatic Cancer|Adenocarcinoma|Prostate Cancer

Phase 1: Alopecia|Anorexia|Kidney Cancer|Liver Cancer|Neuroendocrine Carcinoma|Renal Cell Carcinoma|Thrombocytopenia|Neuroendocrine Tumors|Oncology Solid Tumor Unspecified|Hypertension|Anemia|Hypoxia|Neutropenia|Diarrhea|Acute Myeloid Leukemia|Hepatocellular Carcinoma|Islet Cell Adenoma|Islet Cell Carcinoma|Gastrointestinal Cancer|Pancreatic Cancer|Gastrointestinal Stromal Tumors|Esophageal Cancer|Chronic Lymphoid Leukemia|Lymphocytic Chronic B-Cell Leukemia|Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Lymphoma, B-Cell|Myelodysplastic Syndrome|Myelofibrosis|Acute Lymphoid Leukemia|Preleukemia|Myelogenous, Chronic, BCR-ABL Positive Leukemia|Chronic Myeloid Leukemia|Head and Neck Cancer|Melanoma|Prostate Cancer|Squamous Cell Carcinoma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

SUNINET

P2

Completed

Neuroendocrine Tumors

2020-01-10

CTRC 12-0105

P2

Completed

Glioblastoma

2019-01-04

TH-CR-417

P1

Unknown status

Prostate Cancer|Pancreatic Cancer|Squamous Cell Carcinoma|Melanoma|Head and Neck Cancer

2019-01-01

GETNE-1408

P2

Completed

Pancreatic Cancer|Neuroendocrine Tumors

2018-05-31

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