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Tanezumab

Alternative Names: tanezumab, pf-04383119, rn624
Latest Update: 2024-04-22
Latest Update Note: PubMed Publication

Product Description

Tanezumab is a humanized monoclonal IgG2 antibody that blocks NGF from activating trkA receptors on nociceptive neurons. (Sourced from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069623/)

Mechanisms of Action: NGF Inhibitor

Novel Mechanism: Yes

Modality: Antibody

Route of Administration: Intravenous,Subcutaneous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: European Medicines Agency

Approved Indications: None

Known Adverse Events: None

Company: Pfizer
Company Location: NEW YORK NY 10017
Company CEO: Albert Bourla
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Tanezumab

Countries in Clinic: Japan, United States

Active Clinical Trial Count: 2

Highest Development Phases

Phase 3: Musculoskeletal Pain

Phase 2: Neurilemmoma|Neurofibromatoses

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
2019P003201

P2

Active, not recruiting

Neurofibromatoses|Neurilemmoma

2022-09-30

JapicCTI-163141

P3

Active

Musculoskeletal Pain

None

Recent News Events

Date

Type

Title

04/22/2024

PubMed

 Effect size varies based on calculation method and may affect interpretation of treatment effect: an illustration using randomised clinical trials in osteoarthritis.

01/17/2024

News Article

 Osteoarthritis Therapeutics Market to grow by USD 3.96 billion from 2022-2027, North America to account for 32% of market growth - Technavio

12/01/2023

PubMed

 Characterization of adverse joint outcomes in patients with osteoarthritis treated with subcutaneous tanezumab.

10/10/2023

PubMed

 Various Doses of Tanezumab in the Management of Chronic Low Back Pain (CLBP): A Pooled Analysis of 4,514 Patients.

09/28/2023

News Article

 Generic Injectables Market Size, Share, Development, Growth and Demand Forecast 2023 to 2032

05/29/2023

News Article

 Pain Relief Therapeutics Market to Grow Significantly by 2029- Brandessence Market Research

11/29/2022

News Article

 Analgesics Market Size to Worth Around USD 149.3 Billion by 2030

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