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Solcitinib

Alternative Names: solcitinib, gsk-2586184, gsk2586184, gsk 2586184, glpg-0778, glpg0778, glpg 0778
Latest Update: 2022-12-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: JAK1 Inhibitor,JAK2 Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Solcitinib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Psoriasis|Lupus Erythematosus, Systemic

Phase 1: Healthy Volunteers|Colitis, Ulcerative|Lupus Erythematosus, Systemic

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
NCT02000453

P1

Terminated

Colitis, Ulcerative

2014-08-08

22%
2012-001645-41

P2

Terminated

Lupus Erythematosus, Systemic

2014-03-31

2012-002917-20

P2

Completed

Psoriasis

2014-03-24

NCT01953835

P1

Completed

Lupus Erythematosus, Systemic

2014-03-10

22%

Recent News Events

Date

Type

Title

12/01/2022

PubMed

 Pseudolycorine chloride ameliorates Th17 cell-mediated central nervous system autoimmunity by restraining myeloid-derived suppressor cell expansion.

11/01/2022

PubMed

 The efficacy and safety of tofacitinib, peficitinib, solcitinib, baricitinib, abrocitinib and deucravacitinib in plaque psoriasis - A network meta-analysis.

02/25/2022

PubMed

 A Scoping Review on Use of Drugs Targeting the JAK/STAT Pathway in Psoriasis.

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