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Alternative Names: alvimopan, entereg
Latest Update: 2024-03-06
Latest Update Note: Clinical Trial Update

Product Description

Alvimopan is used to help the bowel recover more quickly after bowel surgery, so that you can eat solid foods and have regular bowel movements. Alvimopan is in a class of medications called peripherally acting mu-opioid receptor antagonists. It works by protecting the bowel from the constipation effects of opioid (narcotic) medications that are used to treat pain after surgery. (Sourced from: https://medlineplus.gov/druginfo/meds/a608051.html)

Mechanisms of Action: OPRM Antagonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: United States

Approved Indications: None

Known Adverse Events: None

Company: Bristol-Myers Squibb
Company Location: NEW YORK NY 10016
Company CEO: Giovanni Caforio
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Alvimopan

Countries in Clinic: United States

Active Clinical Trial Count: 1

Highest Development Phases

Phase 3: Bladder Cancer



Trial Status


Primary Completion Date

Probability of Success




Bladder Cancer


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