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Segesterone

Alternative Names: segesterone, ANNOVERA
Latest Update: 2024-09-11
Latest Update Note: News Article

Product Description

Segesterone acetate is available in the United States in a combination contraceptive vaginal ring (Annovera) that releases segesterone acetate and ethinyl estradiol.  (Sourced from: https://pubmed.ncbi.nlm.nih.gov/30371999/)

Mechanisms of Action: GnRH Agonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Vaginal

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: United States

Approved Indications: Pregnancy Outcomes

Known Adverse Events: Migraine Disorders | Abdominal Pain | Headache | Pain Unspecified | Pruritus | Candidiasis | Candidiasis, Vulvovaginal | Metrorrhagia | Vaginal Discharge | Diarrhea | Injuries/wounds Unspecified

Company: TherapeuticsMD
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Segesterone

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Contraception

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
ANNOV3454-3 PMR

P1

Completed

Contraception

2021-06-08

22%
ANNOV3454-2 PMR

P1

Completed

Contraception

2021-01-06

22%

Recent News Events

Date

Type

Title

09/11/2024

News Article

 Contraline & Population Council Announce Option-to-License Agreement for a Revolutionary Male Contraceptive

09/10/2024

News Article

 Médunik Canada and the Population Council join in a research partnership for a potential new treatment for multiple sclerosis

11/30/2023

News Article

 Duchesnay Inc. is seeking Health Canada approval for a segesterone acetate/ethinyl estradiol contraceptive vaginal system, a new option for women

08/09/2023

News Article

 Micron Biomedical Appoints Brian Bernick, MD as Chairman of Its Board of Directors

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