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Emricasan

Alternative Names: emricasan, idn-6556
Latest Update: 2024-07-05
Latest Update Note: News Article

Product Description

Mechanisms of Action: CAAP Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Histogen
Company Location: San Diego CA 92121
Company CEO: Steven J. Mento
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Emricasan

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Cholestasis|Liver Transplant|Hepatitis A|Hepatocellular Carcinoma|Hepatitis, Alcoholic|Liver Diseases, Alcoholic|Non-alcoholic Steatohepatitis|Fatty Liver, Alcoholic|Hepatitis|Liver Cirrhosis|Hypertension, Portal|Liver Cirrhosis, Alcoholic|Hepatitis, Chronic|Type 1 Diabetes|Hepatitis C, Chronic|Liver Failure, Acute|End Stage Liver Disease|Acute-On-Chronic Liver Failure|Hepatic Insufficiency

Phase 1: Intestinal Diseases|COVID-19|Kidney Diseases

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
EMR-COV-PR001

P1

Terminated

COVID-19

2021-05-28

70%
ENCORE-LF

P2

Unknown status

Liver Cirrhosis

2019-08-01

23%
CON-EX-0217

N/A

Terminated

Liver Cirrhosis

2019-07-15

2015-004473-32

P2

Completed

Hypertension, Portal|Non-alcoholic Steatohepatitis|Liver Cirrhosis|Hepatitis, Alcoholic

2019-04-08

Recent News Events

Date

Type

Title

07/05/2024

News Article

 Zika Virus Therapeutics Market size is set to grow by USD 4.17 billion from 2024-2028, Availability of serology kit for qualitative diagnosis of zika virus infection to boost the market growth, Technavio

06/01/2024

PubMed

 The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury.

03/14/2024

PubMed

 Small Molecules for the Treatment of Long-COVID-Related Vascular Damage and Abnormal Blood Clotting: A Patent-Based Appraisal.

01/28/2024

PubMed

 Biomaterials Functionalized with Inflammasome Inhibitors-Premises and Perspectives.

07/05/2023

News Article

 Histogen to Explore Strategic Alternatives

04/20/2023

News Article

 Histogen Announces Online Publication in the Journal of Investigative Dermatology

04/20/2023

News Article

 FUJIFILM Wako Chemicals U.S.A. Commercializes CEPT Cocktail for Research-Use iPSC Applications

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