Drug Search Results

Eleclazine

Alternative Names: eleclazine, gs-6615
Latest Update: 2023-06-19
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Sodium Channel Blocker

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Gilead Sciences
Company Location: FOSTER CITY CA 94404
Company CEO: Daniel P. O’Day
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Eleclazine

Countries in Clinic:

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Cardiomyopathy, Hypertrophic|Long QT Syndrome

Trial	Phase	Trial Status	Disease	Primary Completion Date	Probability of Success
2019-003958-86	P2	Active, not recruiting	Cardiomyopathy, Hypertrophic\|Long QT Syndrome	2023-02-28

Recent News Events

Date	Type	Title
06/19/2023	PubMed	Late sodium current in synergism with Ca2+/calmodulin-dependent protein kinase II contributes to β-adrenergic activation-induced atrial fibrillation.
10/01/2022	PubMed	QTc interval and ventricular action potential prolongation in the Mecp2Null/+ murine model of Rett syndrome.
05/20/2022	PubMed	Delayed Ventricular Repolarization and Sodium Channel Current Modification in a Mouse Model of Rett Syndrome.

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