Product Description
Pyronaridine (PYR) is an erythrocytic schizonticide with a potent antimalarial activity against multidrug-resistant Plasmodium. The drug is used in combination with artesunate for the treatment of uncomplicated P. falciparum malaria, in adults and children. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/33280083/)
Mechanisms of Action: Hematin Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: Philippines | Vietnam
Approved Indications: None
Known Adverse Events: None
Company: Shin Poong
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Burkina Faso, Gabon, Gambia, Kenya, Korea, Mozambique, Uganda, United Kingdom, Zambia
Active Clinical Trial Count: 4
Highest Development Phases
Phase 2: COVID-19|Communicable Diseases|Malaria|Malaria, Falciparum
Phase 1: Pregnancy Outcomes
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
CAPTURE 1 | P2 |
Active, not recruiting |
Malaria, Falciparum |
2024-12-01 |
|
CAPTURE-2 | P2 |
Recruiting |
Communicable Diseases|Malaria |
2024-11-30 |
|
SP-PA-COV-204 | P2 |
Completed |
COVID-19 |
2022-09-06 |
25% |
MMV_SMC_21_01 | P1 |
Completed |
Malaria|Pregnancy Outcomes |
2022-05-31 |