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Pyronaridine

Alternative Names: pyronaridine
Latest Update: 2024-12-06
Latest Update Note: Clinical Trial Update

Product Description

Pyronaridine (PYR) is an erythrocytic schizonticide with a potent antimalarial activity against multidrug-resistant Plasmodium. The drug is used in combination with artesunate for the treatment of uncomplicated P. falciparum malaria, in adults and children. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/33280083/)

Mechanisms of Action: Hematin Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Philippines | Vietnam

Approved Indications: None

Known Adverse Events: None

Company: Shin Poong
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Pyronaridine

Countries in Clinic: Burkina Faso, Gabon, Gambia, Kenya, Korea, Mozambique, Uganda, United Kingdom, Zambia

Active Clinical Trial Count: 4

Highest Development Phases

Phase 2: COVID-19|Communicable Diseases|Malaria|Malaria, Falciparum

Phase 1: Pregnancy Outcomes

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

CAPTURE 1

P2

Active, not recruiting

Malaria, Falciparum

2024-12-01

CAPTURE-2

P2

Recruiting

Communicable Diseases|Malaria

2024-11-30

SP-PA-COV-204

P2

Completed

COVID-19

2022-09-06

25%

MMV_SMC_21_01

P1

Completed

Malaria|Pregnancy Outcomes

2022-05-31

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